Collocations for breakthrough - noun

big, crucial, great, historic, huge, important, major, real, significant
new, recent
diplomatic, medical, political, scientific, technological

be, represent
achieve, make
We have achieved a real breakthrough in the search for peace.

come, happen
The crucial breakthrough came almost by accident.

breakthrough for
The new deal represents a major breakthrough for the company.

breakthrough in
a significant breakthrough in computer design

the latest breakthrough
the latest breakthrough in biotechnology