Collocations for handicap - noun

serious, severe
mild
mental, physical, visual
She can't drive because of her visual handicap.

be born with, have, suffer, suffer from
Over a million people in this country suffer from mental handicap.

cause
cope with, overcome
She has managed to overcome her physical handicaps.

despite a/the handicap
Despite her handicap, Jane is able to hold down a full-time job.

big, considerable (esp. BrE), great, major, real, serious, severe
Lack of books was a major handicap.

have, suffer
If you don't speak the language, you'll have a real handicap.

prove
His lack of height can prove a handicap against tall players.

despite a/the handicap
handicap to
This could be a serious handicap to her education.