Quirk is used with these nouns as the subject:
lip, mouth

Quirk is used with these nouns as the object:
eyebrow

personal, personality
odd, strange, weird
annoying
little

have
The system has some odd little quirks.

by a quirk of
By a strange quirk of fate, she later married the first boyfriend she'd ever had.

quirk in
as a result of some quirk in the social order

a quirk of fate