Collocations for refine - verb

slightly
greatly
further
increasingly
constantly, continually, continuously
The information system is constantly refined and updated.

gradually

attempt to, try to
continue to
help (to)

into
Sugar cane is refined into sugar.

highly refined
supplies of the highly refined white sugar

Refine is used with these nouns as the object:
concept, design, estimate, model, ore, search, skill, system, technique, understanding