single-handedly
possibly, potentially, probably
literally

be able to, can
Nothing could save us from disaster.

be unable to
may, might
It's a trick that might just save us from total disaster.

help (to), try to
She helped save my career.

battle to, be determined to, be on a mission to, fight to
Doctors battled to save the little boy's life.

find a way to, manage to
We managed to save the animals from being put down.

from
They saved the paintings from destruction.

an attempt to save sth, an effort to save sth
a last desperate attempt to save his marriage

a battle to save sth, a bid to save sth, a campaign to save sth, a fight to save sth
be responsible for saving sb/sth
He is responsible for saving the lives of the aircrew.

beyond saving
The furniture was beyond saving.

up
I'm saving up to buy a new car.

look to, try to
manage to

for
We're trying to save up for our honeymoon.

on
They're hoping to save on printing costs.

scrimp and save
We scrimp and save to send our children to a private school.

thereby saving
We use video conferencing for our meetings, thereby saving thousands in travel expenses.

brilliantly, superbly
bravely, comfortably

Save is used with these nouns as the subject:
firefighter

Save is used with these nouns as the object:
bother, breath, cash, civilization, country, coupon, document, earth, electricity, embarrassment, energy, environment, expense, file, fuel, hassle, honour, inconvenience, life, mankind, marriage, money, neck, penalty, place, planet, receipt, republic, reputation, sanity, seat, setting, shot, sight, soul, space, strength, time, trouble, victim, whale, wildlife, world