Collocations for significant - adj.

be, prove | become | remain | consider sth (as), deem sth, regard sth as, see sth as, think sth, view sth as
The move was regarded as significant in Japan.

deeply, extremely, highly, particularly, very | fairly, quite | statistically
These differences are not statistically significant.

for
This development proved highly significant for the whole town.

to
rituals which are deeply significant to Christians