completely, quite
Her selfish reaction completely spoiled the party.

rather, slightly, somewhat

hate to, not be going to, not want to
I don't want to spoil things for everyone else.

be a pity to
It would be a pity to spoil the surprise.

try to
not let sth
Don't let the bad weather spoil your trip.

with
He spoils the children with expensive toys.

be completely spoiled, be thoroughly spoiled, be utterly spoiled
Those children are thoroughly spoiled!

spoil sb rotten
My grandparents used to spoil me rotten.

a spoiled brat, a spoiled child

Spoil is used with these nouns as the subject:
meat

Spoil is used with these nouns as the object:
appetite, atmosphere, ballot, chance, child, effect, ending, enjoyment, evening, flavour, friendship, fun, joke, mood, party, plan, surprise, suspense, taste, thing