Collocations for substance - noun

addictive, cancer-causing (esp. AmE), carcinogenic, dangerous, harmful, hazardous, noxious, poisonous, radioactive, toxic
harmless, innocuous
Even innocuous substances can sometimes register a positive result in a drug test.

banned, controlled, illegal, illicit, prohibited
hallucinogenic, mind-altering, psychedelic, psychoactive, psychotropic
performance-enhancing
natural
a natural substance found in the body of animals

synthetic
chemical
inorganic, organic
pure
soluble, volatile
active, inactive, inert
crystalline, fatty, gooey (informal), oily, powdery, slimy, sticky, viscous, waxy
medicinal
foreign, unknown
foreign substances that contaminated the experiments
a bag full of some unknown substance

material
the material substance of which we are made

use
abuse
contain
produce
Some frogs produce toxic substances in their skin.

take
The athletes had taken banned substances.

use
abuse

real
The real substance of the report was in the third part.

added
His disappearance has given added substance to the argument that he stole the money.

have
The image of him that the media have presented has no substance.

add, give sth, lend sth
The letters lent substance to the claims.

lack

in substance
There's no difference in substance between the two points of view.

of substance
Nothing of substance was achieved at the meeting.

with substance
lyrics with substance

without substance
Their allegations were without substance.

substance in
There's no substance in the story.

substance of
the substance of the evidence against him

substance to
There was little substance to his claims.