good
acceptable, adequate, perfect, satisfactory, suitable
healthy
Carob is a healthy substitute for chocolate.

close
imperfect (esp. AmE), poor
The television is a poor substitute for human companionship.

cheap
meat, milk, sugar, etc.

act as, serve as
His teacher acted as a father substitute.

use sth as
produce, provide
The company produces substitutes for engine oil.

teacher (AmE)

substitute for
There's no substitute for hard work.

Substitute is used with these nouns as the object:
word

Substitute is used with these nouns:
goalkeeper, teacher