fine
deep
He had deep wrinkles in his forehead.

facial

have
get
prevent
Is there anything you can do to prevent wrinkles?

erase, get rid of, smooth, smooth out
Botox temporarily erases wrinkles by acting on certain facial muscles.

iron out, smooth, smooth out
I tried to iron out the wrinkles in my shirt.
I went through my presentation to iron out any wrinkles. (figurative)

appear, form
Fine wrinkles started to appear around her eyes.

without a wrinkle
Her skin was still without a wrinkle.

Wrinkle is used with these nouns as the subject:
brow, eye, nose

Wrinkle is used with these nouns as the object:
brow, forehead, nose